You had significant GI side effects on tirzepatide: If titrating tirzepatide was genuinely difficult, adding a third mechanism is unlikely to make that easier
The correct framing: if you start compounded semaglutide (Roco or otherwise), adhere to the full titration protocol, tolerate the medication, and remain on treatment for 68 weeks, you can expect to lose 12-15% of your starting body weight
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[DOI] [PubMed] [Google Scholar] 178.Cerulli N., Campanella L., Grossi R., Politi L., Scandurra R., Soda G., Gallo F., Damiani S., Alimonti A., Petrucci F., et al
We find the research compelling it's why we formulated with this ingredient