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Berberine not only enriches butyrate-producing bacteria and elevates butyrate levels, thereby improving gut microbiota composition and function, (86) but also attenuates inflammatory responses and endoplasmic reticulum stress induced by HIV protease inhibitors

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Low-Dose Chronic Exposure Effects Present Assessment Challenges EEDs frequently exhibit non-monotonic dose-response (NMDR) patterns, where low-dose chronic exposure may produce more pronounced biological effects than acute high-dose exposure

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