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Analytical workflows must be deliberately optimized to maintain sensitivity while preserving structural information, ensuring that lipidated regions are fully characterized without inducing degradation or signal loss

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The authors noted that a key limitation of the study is that it was based on US population data and therefore may not be generalizable to countries with lower rates of obesity and metabolic disease

doi:10.1038/ejcn.2017.132 Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P