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In blood pressure studies, NaBPC157 (without effect on basal normal values) compared with L-arginine has both a mimicking effect (impaired L-NAME-blood pressure increase, applied prophylactically and decreased already raised L-NAME values, given at the time of the maximal L-NAME-blood pressure increase (i.e., 10 minutes after L-NAME)) and a preventative activity (L-arginine-induced moderate blood pressure decrease was prevented by NaBPC157 pre-treatment)

10.1016/S2468-1253(19)30342-5 116 SatyanK

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Both peptides are generally well tolerated when used responsibly