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Confirmed fibromyalgia was present only in 1 patient with the most severe form of cEDS, carrying a structural mutation in COL5A2 (Patient 14 in Additional Table 1), who also suffered from recurrent muscle hematomas and ruptures

The best way to support them is to stay hydrated, avoid air pollution and second-hand smoke, and engage in moderate cardiovascular exercise like walking or cycling, which helps improve lung capacity and function.

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95% CI, 1.021.80) and text-combined interventions (RR, 1.53