It has been reported that p53 mutant lung cancer patients exhibited increased expression of immune checkpoint regulators, enhanced CD8 T cell infiltration and increased expression of effector T cell and interferon- associated genes [194]
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Following a story arc on the Julianne Margolies hit "The Good Wife" (CBS 2009-2016), Tierney returned to full-time TV work as one of the stars of "The Affair" (Showtime 2014- ), winning a Golden Globe for her work in 2016
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