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Third, although our study showed significant changes in ion channel function and the expression of inflammation and airway cell markers in response to PG/VG aerosols after seven days, longer-term exposures may be necessary to mimic the effects of chronic e-cig use in humans

Examples: Classic "codger" style blends often fit here, though some can be heavier

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(Even those associations that are making a difference are frequently very new.) There are also internal differences