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Compared with case-control studies [39, 40], prospective studies may lose some statistical power, but estimates of the absolute risk support using the PRS to predict incident lung cancer [10, 41]

Because carrier guidelines for vaping are less standardized than for cigars or smokeless tobacco, prescreening across multiple carriers before any formal submission is particularly valuable both to identify which carriers offer the most favorable vaping classification and to avoid the mistake of submitting to a strict carrier that will produce an inflated offer or a decline that follows the applicants MIB record into subsequent applications

For smokers with a family history of baldness, nicotine can be a significant trigger that speeds up the progression of permanent hair loss

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The levels of HPHCs [32,33,34] emitted by a cMRTP can thereby be compared with those emitted by a reference cigarette such as 3R4F from the University of Kentucky