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Nicotine pouches should not be used by persons with reduced physical, sensory or mental capabilities or lack of knowledge, unless they have been given supervision or instruction to use the product in a safe way and understand the hazards involved

In July 2020, the FDA ordered Puff Bar to "remove their flavored disposable e-cigarettes and youth-appealing e-liquid products from the market because they do not have the required premarket authorization." Puff Bar responded by reformulating its products, which now contain synthetic nicotine

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A., Hann, N., Wilson, A., Mnatzaganian, G