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"Underpinned by compelling strategic and financial rationale, this combination would create a global smoke-free champion -- strengthened by complementary geographic footprints, commercial capabilities and product portfolios -- and open up significant platforms for growth in the US and internationally," he said

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A non-treatment extension phase of this study examined rate and onset of cardiovascular events and found no significant difference in time to onset of major adverse cardiovascular events with varenicline or bupropion versus placebo [58]