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Current UK guidance from NICE does not specifically list smokeless tobacco as a primary cause of NAFLD, though tobacco cessation is recommended as part of overall liver health strategies

One complication associated with chewing tobacco is an increased risk of several types of cancer, including bladder cancer

However, smoking impairs this regenerative capacity by affecting liver cell proliferation and survival, slowing down recovery from liver injuries

Highlighting that chewing tobacco can cause cancer faster than cigarettes can motivate users to reconsider their habits

Observational studies show associations between tobacco use and increased rates of non-alcoholic fatty liver disease, but more research specific to smokeless tobacco is needed to fully characterise this relationship