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As the biologically active fragment Ac-SDKP, it is primarily studied for its roles in actin upregulation and cellular mobility, angiogenesis and new blood vessel formation, collagen architecture and extracellular matrix remodeling, reduction of fibrotic scarring in soft tissue models, and systemic recovery signaling across multiple tissue types

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2008: EMD Serono discontinued commercial production of GEREF for reasons unrelated to its safety or effectiveness

AOD 9604 is supplied as a lyophilized powder to support stability during storage and shipping

However, regular use over several days or weeks may be necessary for therapeutic advantages such tissue healing or inflammation reduction